BACTERIAL CNS FLOW CHIP:
Simultaneous detection of a panel of bacteria causing meningitis:
CNS Viral:
Simultaneous detection (in one step RT-PCR) of a panel of DNA and RNA viruses causing neurological infections:
Simultaneous detection of a panel of pathogens responsible for sepsis, including, Gram + Coccus, Gram – Bacillus, Fungi, and antibiotic resistant forms, MRSA, mecA, vanA, vanB, ESBL, and Carbapenemases (covered by a patent).
Gram + Coccus:
Gram – Bacillus:
HPV DIRECT FLOW CHIP
Simultanous detection and genotyping of HPV:
Master Diagnostica offers the following hybridization systems based on the DNA Flow Technology:
hybriSpot 24TM: Hybridization system fully automated; 24 samples
hybriSpot 12TM: Hybridization system semi-automated; 12 samples
e-BRID SYSTEMTM: Hybridization system fully automated; 15 samples
Common features:
Based on the DNA Flow Technology
Hybridization method: Reverse dot-blot
Supported by hybriSoft (sample management software)
Automated:
Reagent dispenser (robotic arm)
Temperature
Image-capture
Integrated instrument for PCR and hybridization (under development)
Ability toperformtwotechniques at the same time
Bar-code identification of reagents and samples (strips)
Comprehensive process control by sensors (vacuum; levels; temperature)
UV light for DNA decontamination
For more information click here
Semi-automatic:
Temperature and time controls
Maximum 12 samples
Programmed buzzer to indicate the end of each step
Monitor screen to control temperature and time
Pneumo CLART bacteria is an in vitro diagnostics product for detecting and characterizing multiple bacteria causing repiratory tract infections. Simultaneous detection is performed by multiplex PCR and subsequent visualization in low-density arrays, based on CLART Technology.
Analysis information
Pneumo CLART bacteria detects the presence of pathogenic and potentially pathogenic bacteria in resp
iratory samples as BAL, BAS, lavages, sputum…
The rapid detection of bacteria allows the clinician to adjust the antimicrobial therapy, thus improving patie
nt’s health and recovery perspectives, as well as reducing associated costs due to prolonged hospitalization or non-effective therapies.
Pneumo CLART bacteria is able to detect the following targets when present in the sample:
Implementation of new molecular technologies in the diagnosis of bacterial respiratory infections considerably reduces the drawbacks of the main traditional detection systems as:
Low sensitivity of some cultures media.
Turnaround time to results.
Highly specific transport media.
Pneumo CLART bacteria has been developed and validated for detection of aforementioned bacterial in the following samples:
Sputum.
Nasopharyngeal lavage, exudate and aspirate.
Broncoalveolar lavage (BAL).
Broncoaspirate (BAS).
Sensitivity and specificity
The presence of 120 hybridization probes within the array, allows to identify each target at least in triplicate. This ensure specificity and sensitivity of the analysis.
Quality control
Pneumo CLART bacteria guarantees the quality of the results by including three quality controls in the amplification tubes, thus achieving considerable savings in reagents for parallel checks:
Amplification control on the amplification tube: prevent false negative results.
Endogenous genomic control: certifies the effectiveness of the extraction process.
Biotin markers: they have a dual aim; firstly, act as reference system for the automatic alignment of the array grid and, secondly, serve as control of the reagents performance provided for the visualization step.
Automatic reading and interpretation of results
Analysis of results is performed in a gully automatic way by SAICLART, the GENOMICA image processing software for microarrays. This software can automatically detects and interpret all the targets present in the image, thus avoiding any subjectivity that might be introduced by the user intervention. The user thus obtains the results in a fast, simple and reproducible way, presented in clear and concise reports that can be printed or exported to the laboratory information management system.
CLART STDs is an in vitro diagnostics product used for the detection and typing of bacteria, fungi and parasites causing Sexually Transitted Infections (STIs) of the urogenital tract. Simultaneous detection is performed by multiplex PCR and subsequent visualization in low-density arrays, based on CLART Technology.
Analysis information
CLART STDs detects genetic material extracted from urine or swabs samples. This will get a reduction in overall time of diagnosis, more than 24 hours in many cases, allowing the physician to make adjustments in medication and / or therapies administered to each patient.
Microorganism detected with CLART STDs
The use of molecular techniques in the detection of sexually transmitted infections reduces the main limitations and disadvantages of conventional detection methods:
Sensitivity variations observed with different diagnostic methodologies.
Low sensitivity to slow-growing microorganisms.
Antibody titer variations due to antiretroviral treatments.
Validated sample types
The kit CLART STDs has been developed and validated for the detection of different causative agents of STDs in the following samples:
Urine.
Swabs: cervical, vaginal, urethral and rectal.
High sensitivity and specificity
The presence of 120 hybridization probes within the array, make it possible to identify, each target at least in triplicate. This ensures specificity and sensitivity of the analysis.
Analysis of results is performed in a fully automatic way by SAICLART, the GENOMICA image processing software for microarrays. This software can detect and interpret all the targets present in the image, thus avoiding any subjectivity that might be introduced by the user. The user thus obtains the results in a fast, simple and reproducible way, presented in clear and concise reports that can be printed or exported to the laboratory information management system.
CLART EnteroBac detects the presence in stool samples of the main types of Bacteria that produce endotoxins and cause diarrhea. Detection technique is based on our CLARTTechnology, and includes genetic amplification and visualization in low density microarrays.
CLART EnteroBac offers the following advantages compared with other classic identification techniques (stool culture):
CLART EnteroBac system is compatible with automated nucleic acids extractors.
CLART EnteroBac kit has been designed and validated for using stool samples.
Analysis of results is performed in a fully automatic way by SAICLART, the GENOMICA image processing software for microarrays. This software can automatically detect and interpret all the targets present in the image, thus avoiding any subjectivity that might be introduced by the user.The user thus obtains the results in a fast, simple and reproducible way, presented in clear and concise reports that can be printed or exported to the laboratory information management system.
CLART PneumoVir and CLART PneumoVir 2 are an in vitro diagnostics product for the detection and genotyping of multiple viruses that cause respiratory infections, by means of multiplex PCR followed by visualization in low-density arrays, based on CLART® technology.
Analysis information
Both Kits simultaneously detects and subtypes multiple respiratory viruses in a single trial. The information obtained allows a rapid and a proper management of infection avoiding both, the unnecessary and unspecific use of antibiotics as well as the generation of potential resistances.
Similarly, it enables a reduction in diagnosis costs by bringing together multiple targets in a single assay.
Advantages of CLART PneumoVir 2
2 hours less of analysis time compared with CLART PneumoVir
A new tube for detection of Coronavirus OC43 and NL63 and H7N9 subtype of Influenza A
CLART PneumoVir and CLART PneumoVir 2 have been developed and validated for the detection of different respiratory viruses types present in the following samples:
Both kits have sensitivity and specificity values higher than 90%, that are a consequence of the presence within the array of each virus-specific probe in triplicate.
Quality control
CLART PneumoVir and CLART PneumoVir 2 ensures the quality of the results by including internal controls in each test:
Amplification control in each amplification tube: avoid false negative results.
Biotin markers: they have a dual aim; first, they act as reference system for the automatic alignment of the array grid and, secondly, they serve as control of the reagents performance.
Automatic reading and interpretation of results
Analysis if results is performed in a fully automatic ways by SAICLART, the GENOMICA image processing software for microarrays. This software can automatically detect and interpret all the targets present in the image, thus avoiding any subjectivity that might be introduced by the user. The user thus obtains the results in a fast, simple and reproducible way, presented in clear and concise reports that can be printed or exported to the laboratory information management system.